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2024-03-01
The project of human organ-on-chip and multimodal precision measurement method construction selected as one of China’s Top 10 Science Advances in 2023
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2024-01-01
The Center of NMPA issued the Technical Guidelines on Non-clinical Studies of Human Stem Cell-based Products, which explicitly includes new technologies such as organoid into the evaluation models for non-clinical studies of human stem cell-based
2023-08-01
The first space OoC culture experiment in Chinese’s space station, also the first international Taikonaut-Blood-Vessels-on-a-Chip study
2023-05-01
HRS-1893 tablets were approved for clinical trials, which is the first breakthrough of organoid data outside the realm of CGT drugs
2022-12-01
U.S. President Biden signed into law the FDA Modernization Act 2.0, eliminating federal mandatory requirement for animal testing for new and generic drugs
2022-08-01
General Technical Requirement of Skin-on-a-chip, China’s first draft technical standard for OoCs, was published
For the first time, the FDA had approved the clinical trial of an investigational therapy based solely on preclinical efficacy data obtained in human OoC studies
2022-06-01
The U.S. House of Representatives passed the Food and Drug Amendments of 2022, which includes OoCs and Microphysiological Systems (MPSs) as independent systems for evaluating drugs in non-clinical trials
2021-01-01
Organoid research has been approved as a key special project of the National Key R&D Program in China’s 14th Five-Year Plan
The Center of NMPA published the Technical Guidelines on Nonclinical Studies of Genetically Modified Cell Therapy Products, allowing for the use of cell- and tissue-based models to provide useful supplemental information for efficacy and safety evaluation
2020-02-01
Southeast University in China developed a bronchial-lung-on-chip that could be used for the evaluation of COVID-19 infections and treatments, and applied it at the Jiangsu Provincial Center for Disease Control and Prevention